Cervastor

Natural Cerebro and Cardio Vascular protector.
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Product Overview

CERVASTOR is a comprehensive traditional and complementary alternative medicine (CAM) comprising of Red Yeast Rice & Ginkgo Biloba powered by potent anti-oxidants from Green Tea Polyphenol and Tomato Extracts. Each 500mg capsule contains 390mg Red Yeast Rice/Monascus purpureus (providing 1.95mg of monacolin K), 40mg standardized Ginkgo Biloba Extract, 40mg Green Tea Extract and 30mg Tomato Lycopene Extract to help lower bad cholesterol (LDL-cholesterol), promote blood circulation, mental alertness, prevent peroxidation of LDL-cholesterol and act as potent free radical scavenger.

Red yeast rice has been used as medicinal food for a thousand years to improve blood circulation by decreasing cholesterol and triglycerides by inhibiting HMG-CoA (5-hydroxy-3-metylglutaryl-coenzyme A) Reductase.
Traditionally, each 2.4g red yeast rice contains 4.8mg (0.2%) monacolin K and has been recognaized as natural lovastatin as it works similar to statin drug with excellent safety profile. The range can be from 0% - 0.58%, thus not all red yeast rice products work the same way in lowering cholesterol. Each capsule of CERVASTOR contains 1.95mg of monacolin K.

CERVASTOR is useful and recommended to people with the following health related problems:

  • High LDL-cholesterol with and without statin drug
  • People at risk or with signs of senile and dementia
  • People complaining of compromised or poor blood circulation
  • People at risk of stroke, hypertension and heart attack
Effect of Monascus purpureus in Post MI Patients

Ref: Matthew Klimek, Shan Wang and Adeleye Ogunkanmi. Safety and Efficacy of Red Yeast Rice (Monascus purpureus) as an Alternative Therapy for Hyperlipidemia. P.T. 2009 June; 34(6): 313-327 in www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2697909

About Cervastor

Ingredients

Each 500mg capsule contains 390mg Red Yeast Rice/Monascus purpureus (providing 1.95mg of monacolin K), 40mg standardized Ginkgo Biloba Extract, 40mg Green Tea (Camellia sinesis) Extract and 30mg Tomato Lycopene Extract.

Health Benefits

Lu et.al conducted a randomized, double-blind ,placebo-controlled clinical trial of 4,870 Chinese subjects over 4.5 years with myocardial infarction (MI) within 60 months of enrolment. Treated subjects were given 300mg Red Yeast Rice capsule containing 2.5-3.2mg of lovastatin (monacolin K). Thus, patient will obtain sufficient monacolin K ( 3.9mg) by consuming 2 capsules of CERVASTOR daily.

Effect of Monascus purpureus in Post MI Patients

Results:
82% lower of frequency of MI death as compared to placebo (-10.4% vs -5.7%, p<0.001)
33% reduction in the need of revascularization as compared to placebo, p=0.004
Total cholesterol -10.9%, LDL -17.6% as compared to placebo, p<0.001

Direction of Use

1-2 capsules daily after dinner; maximum dosage: 2 capsules three times daily.

Mode of actions

Monascus purpureus Extract

Red yeast rice has been used as medicinal food for a thousand years to improve blood circulation in China by decreasing LDL-cholesterol and triglycerides by inhibiting HMG-CoA (5-hydroxy-3-metylglutaryl-coenzyme A) Reductase via its active compound, monacolin K which is known as “natural lovastatin”. Also reduces triglyceride and apolipoprotein B.

Uses based on Good & Strong scientific evidence:
  • Hyperlipidemia and blood circulation
  • Nephrotic dyslipidemia
    • M purpureus (600mg)-fluvastatin (20mg)-placebo-controlled study up to 1 year showed similar reduction in LDL-C level: Fluvastatin(31%) and M.purpureus (34%) and significant reduction in proteinuria: Fluvastatin (Baseline: 8.3g/day, 1 year: 2.4g/day) and M.purpureus (Baseline: 8.6g/day, 1 year: 3.2g/day), but not in the placebo group
  • Long term use may help reduce the frequency of
    • Myocardial infarction death
    • The need of revascularization

Ginkgo Biloba Extract

  • Prevents further brain damage because it increases levels of an enzyme that eliminates free radicals around the stroke site in the brain.
  • Stimulates greater venous tone which helps clear toxic metabolites that accumulate during ischemia
  • Blocks Platelet Activating Factor Type 1 (PAF-1)
Uses based on Good & Strong scientific evidence:
  • Cerebral and peripheral arterial insufficiency & prevention of stroke, claudication, early stage of Alzheimer disease and multi-infarct dementia, retina damage, impotence and vertigo
  • Restoration of vigilance (alertness)

Green Tea Extract

  • Neutralizes free radicals and prevent oxidation of LDL-cholesterol ,thus reduces the build up of plaque in the arteries
  • Recent experimental studies in both animals and humans have shown that increasing polyphenol intake can lower blood pressure in hypertensive subjects, reduce the tendency of the blood to clot and elevate total antioxidant capacity of the blood
Uses based on Good & Strong scientific evidence:
  • Antioxidant and free radicals scavenger
  • Green tea consumption is associated with reduced mortality due to all causes and due to cardiovascular disease

Tomato Extract

  • Lycopene helps protect cholesterol from being oxidized, and many health professionals believe that it is oxidation of cholesterol in the bloodstream that allows it to stick to the inner lining of the arteries and cause plaque formation.
Uses based on Good & Strong scientific evidence:
  • Potent Antioxidant for cardiovascular health
    • The researchers found that a daily dose of lycopene helped lower systolic and diastolic blood pressure and LDL-cholesterol
    • A large Finish study showed that serum lycopene concentration may help lower atherosclerosis and prevention of stroke

产品简介

CERVASTOR 是一个综合性的传统和辅助的另类医药包括红曲米和银杏叶还采用有效的绿茶多酚抗氧化剂和番茄精华.每500毫克胶囊包含390mg红曲米/红曲霉(为1.95毫克的莫纳可林K), 40毫克的标准化银杏叶精华, 40毫克的绿茶精华, 和30毫克的番茄红素精华以帮助降低坏胆固醇 (低密度脂蛋白胆固醇), 促进血液循环, 心理的机敏, 防止低密度脂蛋白胆固醇氧化, 并作为强大的自由基清除剂.

红曲米早已经被使用了约有1000年来作为药用食品, 以改善血液循环由通过降低胆固醇和甘油三酯, 通过抑制HMG-CoA (5-hydroxy-3-metylglutaryl-coenzyme A) 还原酶.

传统来说, 每2.4克的红曲米含有4.8毫克0.2％)的莫纳可林K并已被确认为天然洛伐他汀. 因为它的工作方式相似他汀类药物并具有优良的安全性. 它的范围可从0％ - 0.58％, 因此，并不是所有的红曲米产品以同样的方式工作降低胆固醇. 每粒 CERVASTOR胶囊含有1.95毫克的莫纳可林K.

CERVASTOR 是有用的, 并建议给有关以下健康问题的人:

  • 有和没有使用他汀类药物并有高低密度脂蛋白胆固醇(LDL-C)
  • 那些有老年和老年痴呆症迹象风险的人
  • 那些总是抱怨受损及血液循环差的人
  • 有中风，高血压和心脏病发作高危的人群
Effect of Monascus purpureus in Post MI Patients

关于 Cervastor

成份

每500毫克胶囊含有390mg红曲米/红曲霉(为1.95毫克的莫纳可林K), 40毫克的标准化银杏叶精华, 40毫克的绿茶精华, 和30毫克的番茄红素精华.

健康效益

Lu et.al 对在60个月内报名并患上超过4.5年心肌梗死的4,870华人进行了一个随机过程, 双盲试验, 安慰剂对照临床试验. 治疗对象是给予300毫克的红曲米胶囊含有2.5 - 3.2毫克的洛伐他汀(莫纳可林K). 因此，患者将获得足够的 莫纳可林K (3.9毫克) 通过每天消耗2粒 CERVASTOR.

Effect of Monascus purpureus in Post MI Patients

CERVASTOR使用方法

每日晚饭后1-2粒; 最大用量：每日3次, 每次 2粒.

多重模式的效益

红曲米提取物

红曲米早已在中国被使用了约有1000年来作为药用食品, 以改善血液循环由通过降低胆固醇和甘油三酯, 通过抑制 HMG-CoA (5-hydroxy-3-metylglutaryl-coenzyme A) 还原酶并通过其有效成分, 莫纳可林K也被称为 “自然洛伐他汀”. 还可以减少甘油三酯和载脂蛋白B.

红曲米的用途基于好又强有力的科学证据:
  • 高脂血症与血液循环
  • 肾病血脂异常
    • 红曲米 (600毫克) – 氟伐他汀(20毫克) – 安慰剂对照研究达一年显示类似减少低密度脂蛋白胆固醇水平: 氟伐他汀(31%) 和红曲米 (34%) 而且明显减少蛋白尿: 氟伐他汀 (底线: 一天8.3克, 一年: 一天2.4克) 和红曲米( 底线: 一天8.6克, 一年: 一天3.2克), 但不是在安慰剂组
  • 长期使用可能有助于降低一些频率如:
    • 心肌梗死死亡
    • 心肌血运重建术的需要

银杏叶提取物

  • 防止进一步的脑损伤因为它能增加酶的水平并且消除围绕在脑中风部分的自由基.
  • 刺激更多静脉音, 这有助于清除有毒代谢物其在缺血期间积累的
  • 阻止血小板活化因子1型)
银杏叶的用途基于好又强有力的科学证据:
  • 大脑和周边动脉供血不足与预防中风, 跛行, 早期阶段的阿尔茨海默氏症和多发梗塞性痴呆, 视网膜损害，性无能和眩晕
  • 恢复警惕 (警觉)

绿茶提取物

  • 中和自由基并防止低密度脂蛋白胆固醇氧化, 从而降低在动脉里组成斑块
  • 最近在动物和人类的实验研究指出, 增加摄入多酚可降低高血压者的血压, 减少 血液凝块的趋势并提高血液的总抗氧化能力.
绿茶的用途基于好又强有力的科学证据:
  • 抗氧化和清除自由基
  • 饮用绿茶能够降低有关因各种原因和心血管疾病造成的死亡率

番茄提取物

  • 番茄红素有助于保护胆固醇被氧化, 许多健康专业人士认为,它是胆固醇在血液中氧化并允许它粘在动脉内壁然后导致形成斑块.
番茄提取物 的用途基于好又强有力的科学证据:
  • 有助于心血管健康的抗氧化剂
    • 研究人员发现，每天服用番茄红素有助于降低收缩压和舒张压和低密度脂蛋白胆固醇
    • 一个已完成的大研究表明, 血清番茄红素浓度可能有助于降低动脉粥样硬化和预防中风