- Alimentary System
- Cardiovascular & Hematopoietic System
- Respiratory System
- Neuro-Muscular System
- Hormones
- Contraceptive Agents
- Antibiotics
- Other Chemotherapeutics
- Genito-Urinary System
- Metabolism (Anti-Cholesterol/Osteoporosis)
- Eye, Ear, Mouth & Throat
- Dermatologicals
- Anaesthetics – Local & General
- Allergy & Immune System
- Antidotes & Detoxifying Agents
- Intravenous & Other Sterile Solutions
- Miscellaneous
= Chemical Compound
= Indications
= Dosage
= Contraindication
= Special Precautions
= Adverse Reactions
= Drug-Drug Interaction
Anaesthetics - Local & General
Propofol.
Induction & maintenance of general anaesth, sedation
of ventilated patients receiving intersive care & conscious
sedation for surgical & diagnostic procedures.
Child< 3 yr.
Cardiac, resp, renal or hepatic impairment; hypovolaemic
or debilitated patients; disorders of fat metabolism or
conditions where lipid emulsions should be used cautiously.
Monitor blood lipids in patients at risk. Do not use in
pregnancy, has been used for termination in 1st trimester.
Ability to drive or operate machinery may be affected. Do
not use for obstetric anaesth. Bradycardia. Possible risk
of convulsion if administered to an epileptic patient. Monitor
signs of hypotension, airway obstruction & oxygen desaturation.
Hypotension, transient apnoea, post-op fever. Rarely,
epileptiform movements including convulsions & opisthotonus;
nausea, vomiting, post-op headache. Rarely, discoloration
of urine, thrombosis & phlebitis. Pulmonary edema. Very
rarely, anaphylaxis which may include bronchospasm, erythema
& hypotension. Pain on inj. Sexual disinhibition on
recovery from anaesth.
Halothane.
General anesth.
Unexplained jaundice & pyrexia following previous
exposure to halothane.
Avoid repeated exposure w/in 3 mth. Maintain in lightest
plane possible in obstetric procedures. Use moderate hyperventilation
during neurosurgery. Ensure adequate room ventilation. Pregnancy
& lactation. May impair ability to drive or operate
machinery. Pheochromocytoma, myasthenia gravis.
Bradycardia & hypotension during induction. Cardiac
arrhythmias during anesth. Rarely, malignant hyperpyrexia.
Liver damage. Shivering during recovery. Post-op nausea
& vomiting.
Potentiates action of nondepolarizing muscle relaxants.
Adrenaline, other sympathomimetics & aminophylline &
theophylline may precipitate arrhythmias.
Lidocaine.
Vasal procedures, oral & dental procedure, procedures
in the oropharynx, procedures in the larynx, trachea &
bronchi, O & G, Laryngotracheal use, nasal, oral &
oropharyngeal use.
Observe systemic status of the patient. Use lowest possible
conc & dosage. Avoid contact w/ eyes. Patients w/ wound
or traumatized mucosa in the region of application. CV disease
& heart failure, partial or complete heart attack, elderly
& patients in poor general health, patients w/ low protein-binding
capacity or nephritic syndrome, advanced liver disease.
May impair ability to drive or operate machinery.
CNS effects, circumoral paraesthesia, numbness of the
tongue, light-headedness, hyperacusis, tinnitus. CV effect:
severe hypotension, bradycardia, arrhythmia, CV collapse.
Other local anaesth, agents structurally related to
amide-type local anaesth.
